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18 Table 4 Time to Improvement of Abnormalities in Vitamin B12 Deficiency After Initiation of Treatment A 2005 Cochrane review involving 108 patients with vitamin B 12 deficiency found that high-dose oral replacement (1 mg to 2 mg per day) was as effective as parenteral administration for correcting anemia and neurologic symptoms

This is particularly important in individuals who are unable to absorb vitamin B12 from the gastrointestinal tract due to conditions such as pernicious anemia, atrophic gastritis, or after certain surgeries

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Timing your injection for best results Does when you inject your 50 units matter